Tuesday, November 13, 2018

Updated meta-analysis of survival after extrapleural pneumonectomy versus pleurectomy/decortication in mesothelioma.

General Thoracic and Cardiovascular Surgery 2018 October 29 [Link]

Magouliotis DE, Tasiopoulou VS, Athanassiadi K

Abstract

OBJECTIVE:
We reviewed the available literature on patients with MPM undergoing either extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D).
METHODS:
Original research studies that evaluated long-term outcomes of P/D versus EPP were identified, from January 1990 to July 2018. The 30 and 90 days mortality, along with the 1-, 2-, 3-, 5-year survival, the median overall survival and the complications were calculated according to both a fixed and a random effect model. The Q statistics and I2 statistic were used to test for heterogeneity among the studies.
RESULTS:
Fifteen studies were included, incorporating a total of 1672 patients treated with EPP and 2236 treated with P/D. The 30-day mortality was significantly higher in the EPP group [OR 3.24 (95% CI 1.70, 6.20); p 



source http://www.mesothelioma-line.com/2018/11/13/updated-meta-analysis-of-survival-after-extrapleural-pneumonectomy-versus-pleurectomy-decortication-in-mesothelioma/

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